Allogeneic CAR T cells with Deoxycytidine Kinase Knockdown Demonstrate Resistance to Fludarabine

Read More


Pires, M. et al. Journal for ImmunoTherapy of Cancer. 9,6 (2021). SITC 36th Annual Meeting.

Development of a Clinical-Grade Meganuclease for Allogeneic CAR T Cell Production​

Read More


Lape, J. et al. American Society of Gene and Cell Therapy 2018 Annual Meeting.

Off the Shelf T Cell Therapies for Hematologic Malignancies

Read More


McCreedy, B. J. et al. Best Pract Res Clin Haematol. 2, 166-175 (2018).

ARCUS Gene Editing to Eliminate MELAS-Associated m.3243A>G Mutant Mitochondrial DNA

Read More


Shoop W., et al. American Society of Gene and Cell Therapy 2022 Annual Meeting.

Targeting the Hepatitis BcccDNA with a Sequence-specific ARCUS Nuclease to Eliminate Hepatitis B Virus

Read More


Gorsuch C., et al. American Society of Gene and Cell Therapy 2022 Annual Meeting.

Translation of an AAV-Delivered Gene Editing Approach for Transthyretin Amyloidosis in Animal Models

Read More


Greig, J.A. et al. American Society of Gene and Cell Therapy 2021 Annual Meeting.

Engineering a Self-inactivating Adeno-associated Virus (AAV) Vector for ARCUS Nuclease Delivery

Read More


Li, H. et al. American Society of Gene and Cell Therapy 2020 Annual Meeting.

A Gene Editing Approach to Eliminate Hepatitis B Virus Using ARCUS Meganucleases

Read More


Gorsuch, C. et al. American Society of Gene and Cell Therapy 2020 Annual Meeting.