ARCUS Genome Editing
At Precision BioSciences, we are using our novel ARCUS genome-editing technology to develop a new class of medicines designed to overcome and potentially cure hard-to-treat conditions, including rare genetic diseases.
ARCUS is a novel and proprietary genome-editing platform discovered and developed by scientists at Precision BioSciences. ARCUS uses sequence-specific DNA-cutting enzymes, or nucleases, to insert (knock-in), remove (knock-out), or repair the DNA of living cells and tissues.
ARCUS Targeting of HBV
ARCUS Dual Mechanism:
Eliminates cccDNA and inactivates integrated HBV DNA.
ARCUS Targeting of DMD
An ARCUS gene editor that is designed to excise the ‘mutation hot spot’ region (exons 45-55) of the dystrophin gene with the goal of permanently and safely restoring muscle function.