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Chris Robinson
Optimization of targeted gene insertion using ARCUS nucleases
by Chris Robinson
Specific elimination of m.3243A>G mutant mitochondrial DNA using mitoARCUS
by Chris Robinson
Shifting m.3243A>G heteroplasmy with PBGENE-PMM: Gene editing therapy for primary mitochondrial myopathy
by Chris Robinson
ARCUS-mediated excision of the “hot spot” region of the human dystrophin gene results in functional improvement in a mouse model of Duchenne muscular dystrophy (DMD)
by Chris Robinson
Unique features of ARCUS nucleases enable high efficiency, targeted gene insertion in vivo
by Chris Robinson
Efficient elimination of MELAS-associated m.3243G mutant mitochondrial DNA by an engineered mitoARCUS nuclease
by Chris Robinson
Preclinical efficacy and safety of ARCUS-POL nucleases for chronic hepatitis B: a potentially curative strategy
by Chris Robinson
ARCUS® Shows Promise for
In Vivo
and
Ex Vivo
Therapeutics
by Chris Robinson
AAV-Meganuclease-mediated Gene Targeting Achieves Efficient and Sustained Transduction in Newborn and Infant Macaque Liver
by Chris Robinson
ARCUS Gene Editing to Eliminate MELAS-Associated m.3243A>G Mutant Mitochondrial DNA
by Chris Robinson
Optimization of Hydroxyacidoxidase 1 (HAO1) Targeting ARCUS Nucleases for the Treatment of Primary Hyperoxaluria Type 1 (PH1)
by Chris Robinson
Targeting the Hepatitis B cccDNA with a Sequence-specific ARCUS Nuclease to Eliminate Hepatitis B Virus
by Chris Robinson
Targeting the Hepatitis B cccDNA with a Sequence-Specific ARCUS Nuclease to Eliminate Hepatitis B Virus In Vivo
by Chris Robinson
Meganuclease Targeting of PCSK9 in Macaque Liver Leads to Stable Reduction in Serum Cholesterol
by Chris Robinson
Engineering a Self-inactivating Adeno-associated Virus (AAV) Vector for ARCUS Nuclease Delivery
by Chris Robinson
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