Specific elimination of m.3243A>G mutant mitochondrial DNA using mitoARCUS

by Chris Robinson

Shifting m.3243A>G heteroplasmy with PBGENE-PMM: Gene editing therapy for primary mitochondrial myopathy

by Chris Robinson

ARCUS-mediated excision of the “hot spot” region of the human dystrophin gene results in functional improvement in a mouse model of Duchenne muscular dystrophy (DMD)

by Chris Robinson

Unique features of ARCUS nucleases enable high efficiency, targeted gene insertion in vivo

by Chris Robinson

Efficient elimination of MELAS-associated m.3243G mutant mitochondrial DNA by an engineered mitoARCUS nuclease

by Chris Robinson

Preclinical efficacy and safety of ARCUS-POL nucleases for chronic hepatitis B: a potentially curative strategy

by Chris Robinson

ARCUS® Shows Promise for In Vivo and Ex Vivo Therapeutics

by Chris Robinson

AAV-Meganuclease-mediated Gene Targeting Achieves Efficient and Sustained Transduction in Newborn and Infant Macaque Liver

by Chris Robinson

ARCUS Gene Editing to Eliminate MELAS-Associated m.3243A>G Mutant Mitochondrial DNA

by Chris Robinson

Optimization of Hydroxyacidoxidase 1 (HAO1) Targeting ARCUS Nucleases for the Treatment of Primary Hyperoxaluria Type 1 (PH1)

by Chris Robinson

Targeting the Hepatitis B cccDNA with a Sequence-specific ARCUS Nuclease to Eliminate Hepatitis B Virus

by Chris Robinson

Targeting the Hepatitis B cccDNA with a Sequence-Specific ARCUS Nuclease to Eliminate Hepatitis B Virus In Vivo

by Chris Robinson

Meganuclease Targeting of PCSK9 in Macaque Liver Leads to Stable Reduction in Serum Cholesterol

by Chris Robinson

Engineering a Self-inactivating Adeno-associated Virus (AAV) Vector for ARCUS Nuclease Delivery

by Chris Robinson

A Gene Editing Approach to Eliminate Hepatitis B Virus Using ARCUS Meganucleases

by Chris Robinson