Effective Cell Dose and Functional Attributes of Azercabtagene Zapreleucel (Azer-cel; PBCAR0191) Associated with Allogeneic CAR T-Cell Safety and Efficacy in Patients with Relapsed/Refractory B-Cell Lymphoma

by Maurissa Messier

Precise and simultaneous quantification of mitochondrial DNA heteroplasmy and copy number by digital PCR

by Maurissa Messier

AAV-meganuclease-mediated gene targeting achieves efficient and sustained transduction in newborn and infant macaque liver

by Maurissa Messier

Effective Cell Dose and Functional Attributes of Azercabtagene Zapreleucel (azer-cel; PBCAR0191) Associate with Allogeneic CAR T-Cell Safety and Efficacy in Patients with Relapsed/Refractory B-Cell Lymphoma

by Maurissa Messier

Treating Transthyretin Amyloidosis via Adeno-Associated Virus Vector Delivery of Meganucleases

by Maurissa Messier

Targeting Hepatitis B cccDNA with a Sequence-Specific ARCUS Nuclease to Eliminate Hepatitis B Virus In Vivo

by Maurissa Messier

ARCUS gene editing of Apolipoprotein C3 results in substantial reduction in serum triglycerides in vivo

by Maurissa Messier

Specific elimination of m.3243A>G mutant mitochondrial DNA using mitoARCUS in cultured cells and a novel xenograft mouse model

by Maurissa Messier

Targeting the Hepatitis B cccDNA with a Sequence-Specific ARCUS Nuclease to Eliminate Hepatitis B Virus In Vivo

by Maurissa Messier

Mitochondrial Targeted Meganuclease as a Platform to Eliminate Mutant mtDNA In Vivo

by Maurissa Messier

Rho 1-2 Meganuclease, an Allele-Specific Gene Editing Therapy, Rejuvenates Rod Photoreceptor Structure and Function in a Pig Model of adRP

by Maurissa Messier

Translation of an AAV-Delivered Gene Editing Approach for Transthyretin Amyloidosis in Animal Models

by Maurissa Messier

Long-Term Stable Reduction of Low-Density Lipoprotein in Nonhuman Primates Following In Vivo Genome Editing of PCSK9

by Maurissa Messier

Preliminary Safety and Efficacy of PBCAR0191, an Allogeneic, Off-the-Shelf CD19-Targeting CAR-T Product, in Relapsed/Refractory (r/r) CD19+ NHL

by Maurissa Messier