Jason Holt

Senior Translational Scientist


Jason is a member of the development team at Precision where he is focused on biomarker work and helping transition programs from pre-clinical research into the clinic. He comes to Precision from Selenity Therapeutics, where he was focused on developing targets involved in oncology and peripheral neuropathy. Jason started his professional career at Duke University working on G-protein coupled receptors. From there, he transitioned to industry and began his 15-year journey at GlaxoSmithKline where he worked in several different areas, primarily focusing on nuclear receptor research and skeletal muscle biology. Jason led multiple lead optimization projects looking at the effects of small molecule inhibitors on skeletal muscle regeneration and muscular dystrophy. Jason began his career as a molecular biologist, but then focused his efforts on cell biology and in vivo pharmacology. After graduating from James Madison University in Harrisonburg, Virginia Jason received his Master’s degree in Physiology from the Medical College of Virginia working on the effects of analgesics in the central nervous system. In his free time, Jason can be found watching or playing soccer with his younger daughter, rooting on the Hurricanes with his older daughter, shooting pool with his friends, or exploring North Carolina breweries with his wife.

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